Find Experts

Experts in Infectious Diseases
MIYAGAWA Happei Konstantina Alexandropoulos Richard J. Lamont Juhi Bagaitkar Beatriz Mothe Nikolaos G. Almyroudis  José Esté Carla Renata Arciola Ioannis Androulakis Emily S Barrett Maria Casadellà David A. Scott Shuang Liang Gong Jianhua CHRIS ROMAN MATT STINSON Dr. Alla Adams Sanghamitra Dey Jonathan Claus ARMANDO PAEZ View More
Gene S. Tan

Professor
Infectious Disease Group
Infectious Diseases J. Craig Venter Institute (JCVI)
United States of America

Professor Infectious Diseases
Biography

Gene Tan is an assistant professor at the J. Craig Venter Institute working in the Infectious Disease group. The focus of his research is on virus-host interactions by defining the immunological, molecular and genetic determinants that govern immunity and disease. The aim is to better understand how viruses manipulate the host machinery to replicate and in turn elucidate the mechanisms by which the host counteracts the pathogen. Analyses of virus-host interaction can then facilitate the development of better diagnostic tools, novel therapeutics and vaccines. Prior to his appointment at JCVI, Dr. Tan was a post-doctoral fellow at the Icahn School of Medicine at Mount Sinai working on characterizing the immunological and structural determinants of protection against influenza virus and Zika virus. He received his doctorate from Thomas Jefferson University and his undergraduate degree from the Philadelphia College of Pharmacy and Science.

Research Intrest

Characterization of the structural and immunological determinants of protection against viral pathogens:

List of Publications
Leon PE, He W, Mullarkey CE, Bailey MJ, Miller MS, Krammer F, Palese P, Tan GS. Optimal activation of Fc-mediated effector functions by influenza virus hemagglutinin antibodies requires two points of contact. Proceedings of the National Academy of Sciences. 2016 Oct 4;113(40):E5944-51.
He W, Tan GS, Mullarkey CE, Lee AJ, Lam MM, Krammer F, Henry C, Wilson PC, Ashkar AA, Palese P, Miller MS. Epitope specificity plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity against influenza A virus. Proceedings of the National Academy of Sciences. 2016 Oct 3:201609316.
Experts in United States of America
Jairaj K. Acharya John Belote Wayde Brown Aimée M. Dudley Jon P Mochel Rabaa M. Al-Rousan Chancellor, Renate Karen Lee Abt Lin Li Hui-Hsien Chou Hamed I. Aly Cory K. Adams Mark Ehrensberger Jose Buitrago Gerhard J. Barone Jacquelyne Adams Jon Calabria Shelley Cannady Susan B. Adams Stoica George Daniel E. Acuna Tal Amasay Jason R. Wiles Matthew H Andersen Brian Rothman View More