Francisco Luis Sala Merchán

Principal Investigator
Molecular Neurobiology
The Instituto de Neurociencias de Alicante
Spain

Professor Biochemistry
Biography

Degree: Medicine, Universidad de Valencia, 1980 Ph.D program: Ph. D., Universidad de Alicante, 1985 Posdoctoral Positions: Laboratory of Prof. Paul R. Adams, Dept. Neurobiology & Behavior, State University of New York at Stony Brook, and Howard Hughes Medical Institute, USA, 1987-1989 Previous positions: Assistant Professor of Pharmacology, between May 1989 and March 2002 Current Position: Full Professor of Pharmacology, Universidad Miguel Hernández de Elche

Research Intrest

Research Fields: Ionic channels on plasma membranes focusing on expression, structure-function relationships, pharmacology and kinetic modelling of neuronal nicotinic receptors. Intracellular calcium movements: diffusion models

List of Publications
Sala F. , Hernandez-Cruz A " Calcium diffusion modeling in a spherical neuron: Relevance of buffering properties " Biophysical Journal . 57 , 313 - 324 ( 1990 ) Hernandez-Cruz A. , Sala F., Adams P. R. " Subcellular calcium transients visualized by confocal microscopy in a voltage-clamped vertebrate neuron " Science . 247 , 858 - 862 ( 1990 ) Campos-Caro, A. , Sala, S., Ballesta, J.J., Vicente-Agulló, F., Criado, M., Sala, F. " A single residue in the M2-M3 loop is a major determinant of coupling between binding and gating in neuronal nicotinic receptors. " Proc. Natl. Acad. Sci. . 93 , 6118 - 6123 ( 1996 ) Campos-Caro, A. , Rovira, J.C., Vicente-Agulló, F., Ballesta, J.J., Sala, S., Criado, M., Sala, F. " Role of the putative transmembrane segment M3 in gating of neuronal nicotinic receptors. " Biochemistry . 36 , 2709 - 2715 ( 1997 ) Sala F , Mulet J, Valor LM, Criado M, and Sala S. " Effects of benzothiazepines on human neuronal nicotinic receptors expressed in xenopus oocytes. " British Journal of Pharmacology . 136(2) , 183 - 192 ( 2002 )

Global Scientific Words in Biochemistry