Fadi Akar

Associate professor
Medicine and Cardiology
Mount Sinai School of Medicine
United States of America

Professor Medicine
Biography

Fadi G. Akar, Ph.D. completed his doctoral degree in Biomedical Engineering from Case Western Reserve University and his post-doctoral training in molecular cardiology at Johns Hopkins University. Dr. Akar was subsequently promoted to assistant professor of medicine in the Division of Cardiology at Johns Hopkins University from 2004 to 2007. Dr. Akar joined the Cardiovascular Research Center at the Icahn School of Medicine at Mount Sinai in 2007, where he established the Cardiac Bioelectricity Research Laboratory. The Akar lab is dedicated to uncovering the mechanisms that promote arrhythmias in common structural heart diseases and to develop novel gene-based approaches to prevent these malignant arrhythmias.

Research Intrest

Biophysics, Cardiovascular, Electrophysiology, Gap Junctions, Gene Therapy, Mathematical and Computational Biology, Mitochondria, Oxidative Stress

List of Publications
Akar FG. A formidable (2014) Heart rhythm : the official journal of the Heart Rhythm Society Vol: 11.
Xie C, Kauffman J, Akar FG (2014) Functional crosstalk between the mitochondrial PTP and KATP channels determine arrhythmic vulnerability to oxidative stress. Frontiers in physiology Vol: 5.
Motloch LJ, Akar FG (2015) Gene therapy to restore electrophysiological function in heart failure. Expert opinion on biological therapy Vol: 15.
Motloch LJ, Hu J, Akar FG (2015) The mitochondrial translocator protein and arrhythmogenesis in ischemic heart disease. Oxidative medicine and cellular longevity.
Xie C, Hu J, Motloch LJ, Karam BS, Akar FG (2015) The Classically Cardioprotective Agent Diazoxide Elicits Arrhythmias in Type 2 Diabetes Mellitus. Journal of the American College of Cardiology.Vol: 66.