Erin Eun-Young Ahn

Associate Professor
Oncologic Sciences
Mitchell Cancer Institute
United States of America

Professor Oncology
Biography

Dr. Erin Eun-Young Ahn joined MCI in 2012 after serving as Assistant Project Scientist at the Moores Cancer Center of the University of California San Diego. With a special interest in regulation of gene expression in cancer development and progression, she heads a lab working on transcription factors, RNA-binding proteins and non-coding RNAs in cancer development and progression, with the goal of identifying novel drug targets for cancer therapy. After completing her undergraduate work in Seoul, South Korea, Dr. Ahn received her Ph.D. from the University of Alabama at Birmingham. She is the recipient of numerous professional awards, including international awards for research in leukemia and allied conditions from Lady TATA Memorial Trust, United Kingdom.

Research Intrest

SON-mediated constitutive/alternative RNA splicing and cancer, Roles of non-coding RNAs in cancer development and progression, Regulation of transcription and RNA splicing in cancer stem cells, Identification of novel targets for cancer therapy

List of Publications
Kim JH, Baddoo MC, Park EY, Stone JK, Park H, Butler TW, Huang G, Yan X, Pauli-Behn F, Myers RM, Tan M. SON and its alternatively spliced isoforms control MLL complex-mediated H3K4me3 and transcription of leukemia-associated genes. Molecular cell. 2016 Mar 17;61(6):859-73.
Hickey CJ, Kim JH, Ahn EY. New discoveries of old SON: a link between RNA splicing and cancer. Journal of cellular biochemistry. 2014 Feb 1;115(2):224-31.
Ahn EE, Higashi T, Yan M, Matsuura S, Hickey CJ, Lo MC, Shia WJ, DeKelver RC, Zhang DE. SON protein regulates GATA-2 through transcriptional control of the microRNA 23a∼ 27a∼ 24-2 cluster. Journal of Biological Chemistry. 2013 Feb 22;288(8):5381-8.
Desai S, Liu Z, Yao J, Patel N, Chen J, Wu Y, Ahn EE, Fodstad O, Tan M. Heat shock factor 1 (HSF1) controls chemoresistance and autophagy through transcriptional regulation of autophagy-related protein 7 (ATG7). Journal of Biological Chemistry. 2013 Mar 29;288(13):9165-76.