Deng Yi is an associate professor of the Department of Biology, Southern University of Science and Technology, and vice director of the Department of Biology. She received a postdoctoral training from the National Institutes of Health at the National Institutes of Health (Ph.D.) from the University of Bochum Ruhr. Dr. Deng's research team is dedicated to studying the molecular mechanisms of cell-extracellular matrix interactions and the relationship between cell-extracellular matrix and health and disease.

cellular microenvironment, signal transduction and diseases: cellular and extracellular matrix by cell - matrix adhesion interactions, in turn, causes the actin cytoskeleton remodeling, and signal transduction. Cell - matrix adhesion of the assembly and disassembly caused by cell migration is essential for embryonic development, maintaining cell function and tissue stability. Abnormal cell - matrix adhesion is closely related to tumor metastasis. We aimed to elucidate the molecular mechanism of cell - matrix adhesion, combined with cell biology and biochemical methods to study cell - matrix adhesion in this dynamic process. The current interest is mainly involved in the regulation of integrin function of the adhesive spotted protein complex assembly, depolymerization, and intracellular transport of molecular mechanisms. ILK-PINCH-parvin and kindlin-migfilin-filamin are two important protein complexes that are integrin-mediated cell - mechanism adhesion. ILK-PINCH-parvin as an integrin signal hub, not only the integrin and actin cytoskeletal link bridge, but also with the regulation of multiple signal pathway interaction; and kindlin-migfilin-filamin in the integration of integrins in the key effect. We used microscopes, including the most advanced fluorescence techniques to study the problems at different spatial scales in the cell. Cell biology of islet Beta- cell: the protective effect of Binding immunoglobulin protein (Bip ) on human amylin ( hIAPP ) -induced islet cell injury and its mechanism.