Deborah M. Mullen

Sr. Research Scientist
health services research
HealthPartners Research Foundation
United States of America

Professor Healthcare
Biography

Deborah M. Mullen is a Visiting Assistant Professor, College of Business and Health Administration, University of St. Francis, Joliet, IL.Dr. Mullen has completed PhD, health services research, University of Minnesota, Twin Cities.

Research Intrest

Mixed methods, evaluation, measurement design, health information technology, informatics, health care system design, organizational behavior and theory, outcomes research, patient safety, quality improvement and implementation research.

List of Publications
Barany G, Kneib-Cordonier N, Mullen DG (1987)Int J Pept Protein Res 30:705-739.
DeGraw AJ, Hast MA, Xu J, Mullen D, Beese LS, et al., (2008)Caged protein prenyltransferase substrates: tools for understanding protein prenylation.Chem Biol Drug Des 72:171-181.
Wollack JW, Zeliadt NA, Mullen DG, Amundson G, Geier S, et al., (2009)Multifunctional prenylated peptides for live cell analysis. J Am Chem Soc. 131:7293-7303
Traaseth NJ, Shi L, Verardi R, Mullen DG, Barany G, et al., (2009)Structure and topology of monomeric phospholamban in lipid membranes determined by a hybrid solution and solid-state NMR approach. Proc Natl Acad Sci U S A. 106:10165-10170.
Wollack JW, Zeliadt NA, Ochocki JD, Mullen DG, Barany G, et al., (2010) Investigation of the sequence and length dependence for cell-penetrating prenylated peptides.Bioorg Med Chem Lett 20:161-163.
Mullen DG, Weigel B, Barany G, Distefano MD (2010)On-resin conversion of Cys(Acm)-containing peptides to their corresponding Cys(Scm) congeners. J Pept Sci 16:219-222.
Kyro K1, Manandhar SP, Mullen D, Schmidt WK, Distefano MD, et al., (2010)Photoaffinity labeling of Ras converting enzyme 1 (Rce1p) using a benzophenone-containing peptide substrate. Bioorg Med Chem 18:5675-5684.
Mullen DG, Kyro K, Hauser M, Gustavsson M, Veglia G (2011)Synthesis of a-factor peptide from Saccharomyces cerevisiae and photoactive analogues via Fmoc solid phase methodology. Bioorg Med Chem 19:490-497.
Ochocki JD, Mullen DG, Wattenberg EV, Distefano MD (2011)Evaluation of a cell penetrating prenylated peptide lacking an intrinsic fluorophore via in situ click reaction. Bioorg Med Chem Lett 21(17):4998-5001.
Gaffarogullari EC1, Masterson LR, Metcalfe EE, Traaseth NJ, Balatri E,et al., (2011)A myristoyl/phosphoserine switch controls cAMP-dependent protein kinase association to membranes. J Mol Biol 411:823-836.
Kyro K1, Manandhar SP, Mullen D, Schmidt WK, Distefano MD. (2011)Photoaffinity labeling of Ras converting enzyme using peptide substrates that incorporate benzoylphenylalanine (Bpa) residues: improved labeling and structural implications. Bioorg Med Chem 19:7559-7569.
Khatwani SL, Kang JS, Mullen DG, Hast MA, Beese LS, et al., (2012) Covalent protein-oligonucleotide conjugates by copper-free click reaction.Bioorg Med Chem. 20:4532-4539.
Diaz-Rodriguez V, Mullen DG, Ganusova E, Becker JM, Distefano MD. (2012) Synthesis of peptides containing C-terminal methyl esters using trityl side-chain anchoring: application to the synthesis of a-factor and a-factor analogs. Org Lett 14:5648-5651.
Mullen DG, Verardi R, Porcelli F, Scaloni A, Barany G, et al., (2012) Synthesis and characterization of the 47-residue heterodimeric antimicrobial peptide distinctin, featuring directed disulfide bridge formation. Biopolymers. 98:479-484.
Gustavsson M, Verardi R, Mullen DG, Mote KR, Traaseth NJ (2013) Allosteric regulation of SERCA by phosphorylation-mediated conformational shift of phospholamban. Proc Natl Acad Sci U S A 110:17338-17343.
Vostrikov VV, Gustavsson M, Gopinath T, Mullen D, Dicke AA (2016) Ca(2+) ATPase Conformational Transitions in Lipid Bilayers Mapped by Site-directed Ethylation and Solid-State NMR. ACS Chem Biol. 11: 329-334.