Courtney C. Babbitt

Assistant Professor
Biology and Commonwealth
University of Massachusetts at Amherst
United States of America

Biography

My research is in evolutionary genomics and I am interested in changes in gene regulation over evolutionary time that impact phenotypic change. In particular, I investigate the evolution of cis-regulatory elements, the evolution of gene expression, and noncoding RNA at a genome-wide scale.

Research Intrest

I am also interested in functionally testing specific rapidly evolving cis-regulatory regions. My current research addresses these essential questions in evolutionary biology as they relate to genetic and phenotypic differences between humans and non-human primates. I integrate both computational and experimental approaches to provide a more comprehensive understanding of the functional changes involved in regulatory evolution and how they contribute to phenotypic evolution.

List of Publications
Babbitt, C.C., Warner, L.R., Fedrigo, O., Wall, C.E., Wray, G.A. 2011. Genomic signatures of diet-related shifts in primate evolution. Proceedings of the Royal Society B, 278: 961-969.
Shibata, Y., Sheffield, N., Fedrigo, O., Babbitt, C.C., Wortham, M., Tawari, A.K., London, D., Song, L., Lee, B., Iyer, V.R., Parker, S.C., Margulies, E.H., Wray, G.A., Furey, T.S., Crawford, G.E. 2012. Extensive evolutionary changes in regulatory element activity during human origins are closely associated with altered gene expression and positive selection. PLoS Genetics, 8(6): e1002789.
Babbitt, C.C., Tung, J, Wray, G.A., Alberts, S.C. 2012. Changes in gene expression associated with reproductive maturation in wild female baboons. Genome Biology and Evolution, 4(2): 102-109.