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Chen Hua

Professor
Laboratory of Genome Sciences & Information
Beijing Institute of Genomics
China

Professor Genetics
Biography

Dr. CHEN Hua is a professor and principal investigator of the Population Genetics and Computational Genomics Group at Beijing Institute of Genomics (BIG), Chinese Academy of Sciences (CAS). Dr. Chen received the B.S. and M.S. degrees in Genetics from Fudan University, Shanghai, China in 2001. He received a Ph.D. in Integrative Biology (with emphasis in Computational Genomic Biology) from University of California, Berkeley, USA in December 2007 (advisor: Dr. Montgomery Slatkin). Dr. Chen did postdoctoral research in Harvard Medical School and School of Public Health, and the Broad Institute. He was a research assistant professor in Temple University, USA before joining BIG. Dr. Chen’s expertise is theoretical population genetics. His recent work includes coalescent theory for the joint allele frequency spectrum, the asymptotic coalescent distributions and statistical methods for detecting natural selection (hidden Markov model, XP-CLR etc)

Research Intrest

Computational Genomics, Population Genetics, allele

List of Publications
ana K., Wang S., Tan J., Gerbault P., Wark A., Tan L., Yang Y., Li S., Tang K.,Chen H., Powell A., Itan Y., Fuller D., Lohmueller J., Mao J., Schachar A., Paymer M., Hostetter E., Byrne E., Burnett E., McMahon AP., Thomas MG., Lieberman DE., Jin L., Tabin CJ., Morgan BA. and Sabeti PC. (2013). Modeling Recent Human Evolution in Mice by Expression of a Selected EDAR Variant. Cell. 152 (4): 691-702.
Chen H*. (2015). Population genetic studies in the genomic sequencing era. Zoological Research. 36(1): 1-11.
.Macholdt E., Lede V., Barbieria C., Mpolokab SW., Chen H., Slatkin M., Pakendorfd B., and Stoneking M. (2014). Tracing prehistoric pastoralist migrations: lactase persistence alleles in southern Africa. Current Biology. 24(8): 875-879.
Chen H*, Hey J, Chen K. (2015). Inferring Very Recent Population Growth Rate from Population-Scale Sequencing Data: Using a Large-Sample Coalescent Estimator. Molecular Biology and Evolution. 32(11):2996-3011.
Experts in China
Zhang Xuming Luo Guoqing Wang Tieguan Wei Zhang Zhao Zhidong Li Lihua Xue Lingyun Lai Liangxue Zhenning Wang Li Dujuan HE CHUN Wei Huachen Xu Ying Wei Minjie Chen Kai Xin Zhang town Lin Shuisheng Guo benqing Yang yong Jia Haitao JIANG Ning Li Qiang Rang-Rong Chang Wang Jian Liu Li Ming View More