Charlotte Cunningham-Rundles

Professor
Medicine, Clinical Immunology and pediatrics
Icahn School of Medicine
United States of America

Professor Pediatrics
Biography

Dr. Cunningham-Rundles is the David S. Gottesman Professor of Immunology at the Mount Sinai School of Medicine in New York. She is a Professor of Medicine and Pediatrics, a member of the Immunology institute,  and directs the Immunodeficiency Clinic at Mount Sinai. She is  also the Program Director of the Allergy Immunology Fellowship training program. She received her MD from Columbia College of Physicians and Surgeons,  and her PhD from New York University School of Medicine. Dr. Cunningham-Rundles is an expert in the more than 150 Primary Immune Deficiency diseases, conditions that result from genetic defects of the immune system. Her research has been supported by US Public Health Service, the Food and Drug Administration, and the National Institutes of Health (NIH) Division of Allergy Immunology and Transplantation. Her contributions have been widely recognized, notably the Clinical Immunology Society President's Award, the Boyle Award Immune Deficiency Foundation award, the Abbott Award from the American Society for Microbiology,  and the American Academy Asthma, Allergy, and Immunology Research Award where she has been on the Board of Directors. She is a Past President of the Clinical Immunology Society. Dr. Cunningham-Rundles has served as Chair of Allergy Immunology and Transplantation Committee for the National Institutes of Health and has Chaired the Immunology Review Committee of the National Aeronautics and Space Administration. She served on the Medical Advisory Boards of the Immune Deficiency Foundation, and the Jeffrey Modell Foundation. Dr. Cunningham-Rundles has served on the FDA Blood Safety and Advisory Committee and is the principal investigator of the USIDNET, a research cooperative sponsored by the NIH. She is a member of the International Union of Immunology Sciences Expert Committee on Immune Deficiency.

Research Intrest

Allergy, Apoptosis/Cell Death, Autoimmunity, B Cells, Biodefense, Cellular Differentiation, Dendritic Cells, Immunology, Mucosal Immunology Allergy and Immunology, Clinical and Laboratory Immunology - Pediatrics

List of Publications
Marron TU, Rohr K, Martinez-Gallo M, Yu J, Cunningham-Rundles C (2010) TLR signaling and effector functions are intact in XLA neutrophils. Clinical immunology. Vol: 137.
Cunningham-Rundles C (2010) How I treat common variable immune deficiency.Vol: 116.
Agarwal S, Smereka P, Harpaz N, Cunningham-Rundles C, Mayer L (2011) Characterization of immunologic defects in patients with common variable immunodeficiency (CVID) with intestinal disease. Inflammatory bowel diseases. Vol: 17.
Ahn S, Cunningham-Rundles C (2009) Role of B cells in common variable immune deficiency. Expert review of clinical immunology. Vol: 5.
He B, Santamaria R, Xu W, Cols M, Chen K, etal (2010) The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88. Nature immunology Vol: 11.