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C.F. (Cor) Calkhoven

Professor
Medical Sciences
University of Groningen
Netherlands

Professor Medical Sciences
Biography

C.F. (Cor) Calkhoven, Professor, Faculty of Medical Sciences.Expertise Transcriptional, translational and post-translational control of gene regulation. Moelcular mechansims in ageing, lifespan determination and age-related diseases. Molecular mechanims and metabolic alterations in tumour development.

Research Intrest

Cell Biology, Biochemistry & Molecular Biology, Biology.

List of Publications
Min, W., Bruhn, C., Grigaravicius, P., Zhou, Z-W., Li, F., Krueger, A., ... Wang, Z-Q. (2013). Poly(ADP-ribose) binding to Chk1 at stalled replication forks is required for S-phase checkpoint activation. Nature Communications, 4, [2993]. DOI: 10.1038/ncomms3993
Zidek, L. M., Ackermann, T., Hartleben, G., Eichwald, S., Kortman, G., Kiehntopf, M., ... Calkhoven, C. F. (2015). Deficiency in mTORC1-controlled C/EBP beta-mRNA translation improves metabolic health in mice. Embo Reports, 16(8), 1022-1036. DOI: 10.15252/embr.201439837
In, K., Zaini, M. A., Müller, C., Warren, A. J., von Lindern, M., & Calkhoven, C. F. (2016). Shwachman-Bodian-Diamond syndrome (SBDS) protein deficiency impairs translation re-initiation from C/EBPα and C/EBPβ mRNAs. Nucleic Acids Research, 44(9), 4134-4146. DOI: 10.1093/nar/gkw005
Zaini, M. A., Müller, C., Ackermann, T., Reinshagen, J., Kortman, G., Pless, O., & Calkhoven, C. F. (2017). A screening strategy for the discovery of drugs that reduce C/EBP beta-LIP translation with potential calorie restriction mimetic properties. Scientific Reports, 7. DOI: 10.1038/srep42603
Sin, O., de Jong, T., Mata-Cabana, A., Kudron, M., Zaini, M. A., Aprile, F. A., ... Nollen, E. A. A. (2017). Identification of an RNA Polymerase III Regulator Linked to Disease-Associated Protein Aggregation. Molecular Cell, 65(6), 1096-1108. DOI: 10.1016/j.molcel.2017.02.022

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