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CACCHIONE STEFANO

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Department of Biology and biotechnology
University La Sapienza
Italy

Professor Genetics
Biography

1985 Laurea in Biological Sciences (110/110 cum laude), Sapienza University, Rome 1987-1989 ENI fellowship, Dept. of Genetics & Molecular Biology, Sapienza University. 1995, 1999 Post-doc, Dept. of Biochemistry & Molecular Biology, University of Valencia, Spain 2001-2010 Researcher, Dept. of Genetics & Molecular Biology, Sapienza University. Since 2010 Researcher, Dept. of Biology & Biotechnology, Sapienza University.

Research Intrest

Structure and function of human telomeric chromatin Interplay between telomeric nucleosomes and the human telomeric proteins TRF Epigenetic status of human telomeres Telomere organization in normal and cancer cells Structural organization of drosophila telomeres

List of Publications
Pisano S, Leoni D, Galati A, Rhodes D, Savino M, Cacchione S. The human telomeric protein hTRF1 induces telomere-specific nucleosome mobility. Nucleic acids research. 2010 Jan 7;38(7):2247-55.
Raffa GD, Raimondo D, Sorino C, Cugusi S, Cenci G, Cacchione S, Gatti M, Ciapponi L. Verrocchio, a Drosophila OB fold-containing protein, is a component of the terminin telomere-capping complex. Genes & development. 2010 Aug 1;24(15):1596-601.
Micheli E, Martufi M, Cacchione S, De Santis P, Savino M. Self-organization of G-quadruplex structures in the hTERT core promoter stabilized by polyaminic side chain perylene derivatives. Biophysical chemistry. 2010 Dec 31;153(1):43-53.
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