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Brian P. Rubin

Joint Staff
Cancer Biology
Cleveland Clinic Lerner Research Institute
United States of America

Professor Medical Sciences
Biography

Brian is focused on understanding the pathogenesis of bone and soft tissue cancers, collectively known as sarcomas. We take a comprehensive approach by analyzing actual human tumors, human tumor cell lines, mouse tumor cell lines and mouse models.

Research Intrest

Sarcoma; genetics, oncogene addiction, targeted therapy, pathology, mouse models of human cancer

List of Publications
Rubin BP (2005) A knock-in mouse model of gastrointestinal stromal tumor harboring Kit K641E. Cancer Res 65:6631-6639.
Rubin BP (2002) Molecular targeting of PDGFB by imatinib mesylate (STI571/Gleevec) in a patient with metastatic dermatofibrosarcoma protuberans. J Clin Oncol 20:3586-3591.
Rubin BP (2001) KIT activation is a ubiquitous feature of gastrointestinal stromal tumors. Cancer Res 15:8118-8121.

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Experts in United States of America
Jairaj K. Acharya John Belote Wayde Brown Aimée M. Dudley Jon P Mochel Rabaa M. Al-Rousan Chancellor, Renate Karen Lee Abt Lin Li Hui-Hsien Chou Hamed I. Aly Cory K. Adams Mark Ehrensberger Jose Buitrago Gerhard J. Barone Jacquelyne Adams Jon Calabria Shelley Cannady Susan B. Adams Stoica George Daniel E. Acuna Tal Amasay Jason R. Wiles Matthew H Andersen Brian Rothman View More