Beatrice Gee

Associate Professor
Pediatrics
Morehouse School of Medicine
United States of America

Professor Pediatrics
Biography

POSTGRADUATE: Children's Hospital, Boston, MA Residency: Pediatric Children’s Hospital and Dana Farber Cancer Institute, Boston, MA Fellowship: Pediatric Hematology/Oncology MEDICAL SCHOOL: Tufts University School of Medicine Degree: Doctor of Medicine UNDERGRADUATE: University of California Degree: Bachelor of Arts in Physiology

Research Intrest

Dr. Gee’s lab focuses on dissecting mechanisms leading to cerebral artery stenosis in young children with sickle cell anemia. Children with sickle cell anemia at high risk for stroke have elevated levels of biomarkers of vascular remodeling, cerebral ischemia and activated coagulation. Red cell transfusion therapies reduce stroke risk and the levels of several of these biomarkers, suggesting that they may be involved mechanistically in the development of arterial stenosis and stroke. Identification of highly predictive stroke risk biomarkers will enable personalized medicine with earlier and accurate targeting of intensive therapies to children with sickle cell anemia who most need them.

List of Publications
Hyacinth HI, Gee BE, Adamkiewicz T, Adams RJ, Kutlar A, Stiles JK, Hibbert JM. Plasma Brain Derived Neurotropic Factor and Platelet Derived Growth Factor Levels Are Elevated in Children with Sickle Cell Anemia and Abnormal Transcranial Doppler and/or Stroke.
Gee BE. Biologic complexity in sickle cell disease: implications for developing targeted therapeutics. The Scientific World Journal. 2013 Mar 25;2013.
Hyacinth HI, Adams RJ, Voeks JH, Hibbert JM, Gee BE. Frequent red cell transfusions reduced vascular endothelial activation and thrombogenicity in children with sickle cell anemia and high stroke risk. American journal of hematology. 2014 Jan 1;89(1):47-51.