Aristotle Mendes da Silva

Professor
Morphology
University of Minas
Brazil

Professor Immunology
Biography

He graduated in Biological Sciences from the Federal University of Minas Gerais-UFMG (1993). He obtained titles of Mestre (1996) and Doctor (2000), both in Biological Sciences (Microbiology), by UFMG. He completed postdoctoral studies in the field of signal transduction of cytokines, interferons (IFNs) and innate immunity receptors at the Cleveland Clinic Foundation, USA, from 2000 to 2003. He was a Visiting Researcher at the René Rachou Research Center from 2003-2004. Currently Associate Professor at UFMG. He was a Visiting Professor at the Biochemistry Molecular Biology and Cellular Biology department (BMBCB) at Northwestern University, USA, in 2008, and at the University of Massachusetts Medical School, USA in 2013. He has experience in Cell Biology, Molecular Biology and Immunology working in following topics

Research Intrest

Cell adaptation to proteotoxicity, Signal transduction of cytokines and pathogens, Molecular mechanisms involved in the control of inflammatory response.

List of Publications
Mugge, FLB; Silva, Aristotle M .. Endoplasmic reticulum stress response in the roadway for the effects of non-steroidal anti-inflammatory drugs. Endoplasmic Reticulum Stress in Diseases, v. 2, p. 1-17, 2015.
VILAS BOAS, F.; Silva, Aristotle M .; LIMA, KM; ESTANISLAU, A.; BITTENCOURT, L.; VILELA, MC; Gomes, DA; Souza, LP; TEIXEIRA, MM; BARCELOS, LS. Impairment of stress granule assembly via inhibition of eIF2alpha phosphorylation sensitizes glioma cells to chemotherapeutic agents. Journal of Neurooncology , v. 127, p. 253-260, 2016.
Samudio, R; PEREIRA, L.; ROCHA, CD; BERG, D.; Muniz-Queiroz, T; SANTANNA, HP; Cabrera, L; COMBE, JM; Herrera, P; Jahuira, M; Lion, FB; Lyon, F; PRADO, WA; RODRIGUES, MR; RODRIGUES-SOARES, F.; SANTOLALLA, ML; Zolini, C.; Silva, Aristotle M .; Gilman, RH; Tarazona-Santos, E.; KEHDY, FS. Population, Epidemiological, and Functional Genetics of Gastric Cancer Candidate Genes in Peruvians with Predominant Amerindian Ancestry. Digestive Diseases and Sciences , v. 61, p. 107-116, 2016.