Dr. Anne  Grove  is currently working as a Gregory Cannaday Burns Professor in the Department of Department of Biological Sciences, Louisiana State University , USA. Her research interests includes Bacterial responses to stress.conditions for the bacterium,virulence genes, antibacterial agents,gene expression . she is serving as an editorial member and reviewer of several international reputed journals. Dr. Anne  Grove  is the member of many international affiliations. She has successfully completed his Administrative responsibilities. she has authored of many research articles/books related to Bacterial responses to stress.conditions for the bacterium,virulence genes, antibacterial agents,gene expression .

Bacterial responses to stress When a bacterial pathogen infects a host, the host defends itself by producing toxic compounds and inducing unfavorable conditions for the bacterium. The bacterium in turn responds to the new environmental cues, often subverting host defenses by utilizing host-derived signals to trigger upregulation of virulence genes. We are focusing on bacterial transcription factors that respond to such host-derived signals to control expression of virulence genes. Understanding mechanisms by which bacterial pathogens change gene expression programs in response to the environmental cues associated with host infection is critical for development of antibacterial agents. A major focus is on MarR family transcriptional regulators and the mechanism by which the binding of ligands controls their ability to regulate gene expression. For example, we are currently focusing on how such transcription factors alter gene expression programs in response to oxidative stress or changes in pH. Organization of genomic DNA Genomic DNA in both prokaryotes and eukaryotes is compacted to fit into cellular compartments. We are interested in architectural proteins, so named because a primary function is to induce a specific DNA topology and control DNA compaction. Architectural DNA-binding proteins play important roles in controlling processes such as DNA repair and gene expression. In eukaryotes, failure to regulate these processes correctly may lead to mutagenesis, genomic instability, and cancer. Current goals pertain to the mechanism by which yeast HMO1 stabilizes nucleosomal arrays and the role of HMO1 in DNA repair and regulation of gene activity. Of specific interest is the role of HMO1 in coordinating gene activity in response to signaling by the Target of Rapamycin (TOR) kinase pathway, which is important for regulating cell growth in response to signals such as nutrient limitation and stress.