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Aneel K Aggarwal

Professor
Pharmacology and oncological department
Mount Sinai School of Medicine
United States of America

Professor Oncology
Biography

Dr. Aggarwal is an internationally recognized structural biologist, who earned his PhD in biophysics at Kings College, University of London, in 1984. From 1985 to 1987, Dr. Aggarwal participated in a NATO research fellowship and was also a postdoctoral fellow in the Department of Biochemistry and Molecular Biology at Harvard University. He then became an Assistant Professor at Columbia University before joining the Mount Sinai Medical School. He is currently a Professor in the Department of Structural & Chemical Biology and holds an Endowed Chair as the Mount Sinai Professor in Structural Biology.

Research Intrest

Biophysics and Systems Pharmacology [BSP] Cancer Biology [CAB] Genetics Genomic Sciences

List of Publications
Swan MK, Johnson RE, Prakash L, Prakash S, Aggarwal AK (2009) Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase delta. Nature Struct. & Mol. Biol. 16: 979-986.
Silverstein TD, Johnson RE, Jain R, Prakash L, Prakash S,etal (2010) Structural basis for the suppression of skin cancers by DNA polymerase eta. Nature 465: 1039-1043.
Ummat A, Rechkoblit O, Jain R, Roy Choudhury J, Johnson RE, etal (2012) Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy. Nature Struct. & Mol. Biol. 19: 628-632.
Gómez-Llorente Y, Malik R, Jain R, Choudhury JR, Johnson RE,etal (2013) The architecture of yeast DNA polymerase ζ. Cell reports 5: 79-86.
Gupta YK, Chan SH, Xu SY, Aggarwal AK (2015) Structural basis of asymmetric DNA methylation and ATP-triggered long-range diffusion by EcoP15I. Nature communications.
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