Biography

Almasan interested in the molecular basis of cell death and proliferation control during the genotoxic stress response. Our laboratory is primarily using two human tumor models: (i) Chronic lymphocytic leukemia (CLL) for leukemia, and (ii) prostate cancer, for epithelial tumors.

Research Intrest

Autophagy; apoptosis; cell cycle; DNA damage; DNA repair; cancer therapeutics; radiation therapy; leukemia; epithelial tumors; prostate cancer

List of Publications
Klionsky DJ, …Almasan A, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy, 2016, 12:1-222.
Madanat YF, Smith MR, Almasan A, Hill BT. Idelalisib therapy of indolent B cell malignancies: chronic lymphocytic leukemia and small lymphocytic or follicular lymphomas. Blood Lymphat Cancer, 2016 , 6:1-6.
Zhu H, Almasan A. Development of venetoclax for therapy of lymphoid malignancies. Drug Des Devel Ther, 2017, 11: 685–694