Zuben E Sauna has been a research reviewer with the US Food and Drug Administration since 2009. He is associated with the Department of Hematology where he is involved with the review of plasma-derived and recombinant coagulation proteins that are used as therapeutics. He also leads an active research laboratory. His research interests lie in the next generation of therapeutic proteins and in pharmacogenetics. A key focus of his research activities has been to understand the pharmacogenetic basis of the immune response to protein therapeutics, which can significantly affect the efficacy and safety of these drugs. His laboratory uses the coagulation Factor VIII as a model and exploits a combination of computational, in vitro and ex vivo approaches to understand why some individuals and/or subpopulations develop inhibitory antibodies while others do not. He has over 50 research papers to his credit; his work has been published in high impact publications too. He received his PhD from Poona University, India with subsequent training at the National Cancer Institute, Bethesda, USA. Z Zuben E Sauna has been a research reviewer with the US Food and Drug Administration since 2009. He is associated with the Department of Hematology where he is involved with the review of plasma-derived and recombinant coagulation proteins that are used as therapeutics. He also leads an active research laboratory. His research interests lie in the next generation of therapeutic proteins and in pharmacogenetics. A key focus of his research activities has been to understand the pharmacogenetic basis of the immune response to protein therapeutics, which can significantly affect the efficacy and safety of these drugs. His laboratory uses the coagulation Factor VIII as a model and exploits a combination of computational, in vitro and ex vivo approaches to understand why some individuals and/or subpopulations develop inhibitory antibodies while others do not. He has over 50 research papers to his credit; his work has been published in high impact publications too. He received his PhD from Poona University, India with subsequent training at the National Cancer Institute, Bethesda, USA. Z

Genetics and Molecular Biology