John J. Marini

Physician
pulmonary medicine
HealthPartners Research Foundation
United States of America

Physician Pulmonology
Biography

John J. Marini is a Physician in pulmonary medicine at HealthPartners Medical Group.He had Completed his MD, Johns Hopkins University School of Medicine; residency in internal medicine and fellowship in pulmonary medicine, University of Washington.his research highlights Cardiopulmonary interactions, dynamic hyperinflation, mathematical modeling of respiratory mechanics, modes of ventilation, patient-ventilator interactions, the work of breathing during mechanical ventilation, tracheal gas insufflation, and airway bio-fluids, propagation of lung injury, and pathobiology of ventilator-induced lung injury. Investigative methodology has ranged from highly theoretical mathematical models of invasive and non-invasive mechanical ventilation and gas exchange through bench laboratory testing to laboratory research using small and large animal models of acute lung injury and therapeutic practices. He has also engaged in physiologic investigations involving normal subjects and chronically ill patients, and has helped to develop techniques for improving diagnostic ability at the bedside (e.g., in monitoring and weaning assessment) as well as to implement therapeutic techniques of value to the critically ill patient.

Research Intrest

Cardiopulmonary physiology and management of acute respiratory failure, with an emphasis on patient-ventilator interactions occurring in that clinical setting. In most of his research, he has positioned himself at the interface between basic physiology and clinical medicine to develop insights into advancing clinical practice.

List of Publications
Mesar T1, Martin D, Lawless R, Podbielski J, Cook M (2015) Human dose confirmation for self-expanding intra-abdominal foam: A translational, adaptive, multicenter trial in recently deceased human subjects. J Trauma Acute Care Surg. 79(1):39-46.
Cortes-Puentes GA, Adams AB, Parker ED, Dries DJ, Marini JJ.(2015) Impact of Chest Wall Modifications and Lung Injury on the Correspondence Between Airway and Transpulmonary Driving Pressures.Crit Care Med. 43(8):e287-95.
Cortes-Puentes GA1, Gard K, Keenan JC, Adams A, Dries D, Marini JJ.(2014) Unilateral mechanical asymmetry: positional effects on lung volumes and transpulmonary pressure.Intensive Care Med Exp. 2(1):4.
Marini JJ (2015) Does high-pressure, high-frequency oscillation shake the foundations of lung protection? Intensive Care Med. 41(12):2210-2.
Sprung CL, Cohen R, Marini JJ (2016) Excellence in Intensive Care Medicine.Crit Care Med. 44(1):202-206
Marini JJ (2016) Should We Embrace the "Open Lung" Approach? Crit Care Med. 44:237-238.
Marini JJ, Gattinoni L, Ince C, Kozek-Langenecker S, Mehta RL, et al., (2015) A few of our favorite unconfirmed ideas.Crit Care. 19 :S1.
Marini JJ (2015) Re-tooling critical care to become a better intensivist: something old and something new.Crit Care. 19:S3.
Marini JJ (2015) Advances in the support of respiratory failure: putting all the evidence together.Crit Care. 19:S4.
Gattinoni L, Marini JJ, Pesenti A, Quintel M, Mancebo J, et al., (2016) The "baby lung" became an adult.Intensive Care Med. 42:663-673.
Santos RS, Moraes L, Samary CS, Santos CL, Ramos MB, et al., (2016) Fast Versus Slow Recruitment Maneuver at Different Degrees of Acute Lung Inflammation Induced by Experimental Sepsis.Anesth Analg.122(4):1089-100.
Holets SR, Marini JJ (2016) Is Automated Weaning Superior to Manual Spontaneous Breathing Trials? Respir Care. 61(6):749-760.
Marini JJ, Josephs SA, Mechlin M, Hurford WE (2016) Should Early Prone Positioning Be a Standard of Care in ARDS With Refractory Hypoxemia?Respir Care. 61(6):818-29.
Marini JJ (2016) Strain Rate and Cycling Frequency-The "Dynamic Duo" of Injurious Tidal Stress.Crit Care Med. 44(9):1800-1801.
Marini JJ, Jaber S (2016) Dynamic predictors of VILI risk: beyond the driving pressure.Intensive Care Med. Oct;42:1597-600.
Marini JJ, Hurford WE (2016) Should Early Prone Positioning Be a Standard of Care in ARDS With Refractory Hypoxemia? Wrong Question-Reply.Respir Care. 61(11):1564-1565.
Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, et al., (2017) Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.Crit Care Med. 45:486-552.
Rhodes A, Evans L, Alhazzani W, Levy MM, Antonelli M, et al., (2017) Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.Intensive Care Med. 43:304-377.
Gattinoni L, Cressoni M, Chiumello D, Marini JJ (2017) Transpulmonary Pressure Meaning: Babel or Conceptual Evolution?Am J Respir Crit Care Med. 195:1404-1405.
Gattinoni L, Marini JJ, Collino F, Maiolo G, Rapetti F, et al., (2017) The future of mechanical ventilation: lessons from the present and the past.Crit Care. 21: 183.
Marini JJ (2017)Clinical Deployment of the Esophageal Balloon Catheter-Making the Case.Crit Care Med. 45:1419-1421.
Jaber S, Bellani G, Blanch L, Demoule A, Esteban A, et al., (2017) The intensive care medicine research agenda for airways, invasive and noninvasive mechanical ventilation.Intensive Care Med.