Serena M. Bagnasco

Associate Professor
Pathology
Johns Hopkins Medicine
United States of America

Doctor Pathology
Biography

Dr. Serena Bagnasco is an associate professor of pathology at the Johns Hopkins University School of Medicine. Her areas of clinical expertise include pathology and transplant pathology. Dr. Bagnasco serves as director of the Hopkins Renal Pathology Service. Dr. Bagnasco obtained her M.D. degree from the University of Genova in Italy, and spent several years in the Laboratory of Kidney and Electrolyte Metabolism NIH/NHLBI for her post-doctoral training in kidney physiology. She completed a residency in anatomic pathology at Northwestern University in Chicago, and a clinical fellowship in renal pathology at Johns Hopkins. Her research interests are in the field of renal physiology and pathophysiology. She has studied how renal cells adapt to the environment of the kidney medulla, characterized by high concentration of salt and urea. More recently she has focused on the pathology of renal transplant, and the use of digital pathology in the analysis of kidney biopsies. Dr. Bagnasco is on the editorial board of several peer reviewed journal including The American Journal of Physiology, is Academic Editor for PlosOne. Dr. Bagnasco has authored more than 50 articles in scientific journals.

Research Intrest

Kidney molecular physiology and pathology

List of Publications
Nakayama Y, Peng T, Sands JM, Bagnasco SM. "The TonE/TonEBP pathway mediates tonicity-responsive regulation of UT-A urea transporter expression." J Biol Chem. 2000 Dec 8;275(49):38275-80.
Bagnasco SM, Peng T, Janech MG, Karakashian A, Sands JM. "Cloning and characterization of the human urea transporter UT-A1 and mapping of the human Slc14a2 gene." Am J Physiol Renal Physiol. 2001 Sep;281(3):F400-6.
Peng T, Sands JM, Bagnasco SM. "Glucocorticoids inhibit transcription and expression of the UT-A urea transporter gene." Am J Physiol Renal Physiol. 2002 May;282(5):F853-8.
Bagnasco SM. "Gene structure of urea transporters." Am J Physiol Renal Physiol. 2003 Jan;284(1):F3-10. Review.
Inoue H, Jackson SD, Vikulina T, Klein JD, Tomita K, Bagnasco SM. "Identification and characterization of a Kidd antigen/UT-B urea transporter expressed in human colon." Am J Physiol Cell Physiol. 2004 Jul;287(1):C30-5. Epub 2004 Feb 25.