Lady Davis Institute, Rm 326 Jewish General Hospital
Research Intrest
HIV and host cell interactions
List of Publications
Zeyun Mi, Jiwei Ding, Quan Zhang, Jianyuan Zhao, Ling Ma, Haisheng Yu, Zhenlong Liu, Guangzhi Shan, Xiaoyu Li, Jinming Zhou, Tao Wei, Liguo Zhang, Fei Guo, Chen Liang, and Shan Cen. 2015. A small molecule compound IMB-LA inhibits HIV-1infection by preventing viral Vpu from antagonizing the host restriction factor BST-2. Scientific Reports 5:18499.
Zhen Wang, Qinghua Pan, Patrick Gendron, Weijun Zhu, Fei Guo, Shan Cen, Mark A Wainberg and Chen Liang. 2016. CRISPR/Cas9-derived mutations both inhibit HIV-1replication and accelerate viral escape. Cell Reports 15:1-9.
Chen Liang, Mark A Wainberg, Atze T Das, and Ben Berkhout. 2016. CRISPR/Cas9: a double-edged sword when used to combat HIV infection. Retrovirology 13:37.