Smith leads a laboratory in the Cambridge Institute for Medical Research which studies defects in regulatory control of the immune system that can lead to autoimmunity and alter defence against infection. He also runs a translational programme in autoimmune disease (particularly SLE and vasculitis) that has led to the discovery of a novel prognosis-predicting biomarker now entering clinical trials, and the identification of genes involved in disease pathogenesis. Smith leads a laboratory in the Cambridge Institute for Medical Research which studies defects in regulatory control of the immune system that can lead to autoimmunity and alter defence against infection. He also runs a translational programme in autoimmune disease (particularly SLE and vasculitis) that has led to the discovery of a novel prognosis-predicting biomarker now entering clinical trials, and the identification of genes involved in disease pathogenesis.
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