Dr. Sherman joined Horizon Pharma in June 2009 as executive vice president, development and regulatory affairs and chief medical officer. From June 2011 to Sept. 2014, he served as executive vice president, development, manufacturing, and regulatory affairs and chief medical officer. Since then, he has served as executive vice president, research and development and chief medical officer.

From June 2009 to June 2010, Dr. Sherman also served as president and board member of the Drug Information Association (DIA), a nonprofit professional association of members who work in government regulatory, academia, patient advocacy and the pharmaceutical and medical device industry. Dr. Sherman serves as DIA liaison to the Clinical Trial Transformation Initiative (CTTI), a public-private partnership founded by the U.S. Food and Drug Administration and Duke University to improve the quality and efficiency of clinical trials. He also serves on the board of advisors of the Center for Information and Study on Clinical Research Participation (CISCRP) a nonprofit organization dedicated to educating and informing the public, patients, medical/research communities, the media and policy makers about clinical research and the role each party plays in the process. He is an adjunct assistant professor of medicine at the Northwestern University Feinberg School of Medicine and is a member of a number of professional societies, as well as a diplomat of the National Board of Medical Examiners and the American Board of Internal Medicine.