Igor Koralnik, MD, is chairperson of the Department of Neurological Sciences and head of the Section of Neuroinfectious Diseases at Rush University Medical Center. He is president of the International Society for NeuroVirology and is an internationally recognized expert in the management of neurological complications of HIV infection, as well as a leading researcher in the investigation of polyomavirus JC, the etiologic agent of progressive multifocal leukoencephalopathy, or PML. PML is a deadly demyelinating disease of the brain occurring mainly in immunosuppressed individuals, for which there is no cure. His laboratory has used PML as a model to understand broader principles of neuropathogenesis associated with demyelination, neuronal injury, central nervous system inflammation and seizure development. In addition, Koralnik directs the Neuroimmunology Fellowship Program at Rush University, in which fellows rotate in both the multiple scleroris and neuro-HIV clinics and learn to care for patients over the entire immunologic spectrum. Koralnik has also created a global neurology research program in Lusaka, Zambia, where he and fellows study opportunistic central nervous system infections and new onset seizures in HIV-infected patients.

Neurological Sciences, Management of neurological complications of HIV infections