Research activities of the Centre are focused on topics covered by the Act No.258/2000 Coll. Law, on public health protection, and related Decrees dealing with requirements on health safety of consumer products and their ingredients. Toxicological endpoints such as local toxicity (skin and eye irritation, skin absorption and penetration, skin sensitization), systems toxicity such as acute and repeat dose toxicity, genotoxicity, mutagenicity, carcinogenicity, inhalation toxicity, microbiological safety and others are investigated in relation to the expected route of exposure. Toxicological evaluation is accompanied by top professional chemical analyses identifying chemical contaminants in consumer products such as food contact materials, toys, children products, cosmetics, food additives, special categories of food, food, medical devices, chemicals and chemical preparations and other materials coming into contact with human body.

Research units of the Centre represent integral parts of reference centers and laboratories in the NIPH. They develop new test methods,