Dr. Bhaumik had completed Ph.D IN 2009 FROM Jadavpur University (I.A.C.S.).She is specialized in Organic Chemistry/Synthetic Organic chemistry/Synthesis of optically pure potentially bioactive natural and unnatural molecules from chiral pool precursors.

Natural products, with their enormous diversity in molecular structure and their possible medicinal use, have been and still are the object of intensive investigations by synthetic organic chemists. Nature yields an enormous variety of chiral compounds among its natural products. Determination of the absolute configuration of chiral molecules is an important step in any field related to chirality, especially in the pharmaceutical industry. The body being chiral selective will interact with each enantiomer by a different pathway to show different pharmacological activity. Thus, one isomer may produce the desired therapeutic activities, while the other may be inactive or, in worst cases, produce undesired effects. Hence each enantiomer of the drug should be studied separately for its pharmacological and metabolic pathways. Synthetic organic chemists always face a major challenge in the preparation of optically pure chiral compounds. In our laboratory we engross ourselves in the syntheses of potentially bio-active natural products as well as their synthetic analogues in optically pure form starting from commercially available, inexpensive chiral pool precursors like D-(+)-mannitol. Toward this end assignment of absolute configurations to molecules with hitherto unknown absolute stereochemistry is also attempted. Asymmetric synthesis of potentially bioactive molecules from chiral pool precursors has always been an attractive method because of rich source of chirality and abundance of the chiral pool compounds. Carbohydrates are the most prominent members of the chiral pool as they are widely distributed in nature and are vast reservoir of highly functionalized chirality. Enantiomerically pure fragments are derived from carbohydrates and then these can be used as chiral synthons and incorporated directly into the target molecules.