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Setshaba D. Khanye

Lecturer 
Chemistry
Rhodes University
South Africa

Academician Chemistry
Biography

Lecturer in General Chemistry. The group research focus lies in the field of Bioinorganic and Medicinal Chemistry. The medicinal chemistry efforts are directed toward the causative agents of malaria, tuberculosis and trichomoniasis infections. The objective is to design target–directed inhibitors of molecular chaperons (i.e. Heat Shock Proteins), cysteine proteases, topoisomerase II/IV.

Research Intrest

Physicochemical properties in drug design

List of Publications
Setshaba D Khanye, Gregory S Smith, Carmen Lategan, Peter J Smith, Jiri Gut, et al. (2010) Synthesis and in vitro evaluation of gold(I) thiosemicarbazone complexes for antimalarial activity. J of Inorganic Biochem 104: 1079-1083.
Judy Caddy, E Mabel Coyanis, Manuel A Fernandes, Setshaba D Khanye, Bernard Omondi (2007) Cis-ethylenebis(diphenylphosphine oxide). Acta Crystrallographica Section E, E63: o1387-o1389.
Willem AL van Otterlo, Garreth L Morgans, Setshaba D Khanye, Blessing AA Aderibigbe, Joseph P Michael, et al. (2004) Isomerization and ring-closing metathesis for the synthesis of 6-,7- and 8-membered benzo- and pyrido-fused N,N-, N,O- and N,S-heterocycles. Tetrahedron Lett 45: 9171-9175.

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