Assistant Professor
Department of Biology
Syracuse University
United States of America
Sarah E. Hall is an assistant professor in Department of Biology of Syracuse University, New York United States. She specializes in epigenetic mechanisms that regulate environmental programming of gene expression due to early life stress.
My primary research interest is how environmental experiences early in development can result in altered adult phenotypes, such as changes in behavior or physiology. Environmental experiences in utero or immediately after birth have been linked to various adult diseases in humans, such as metabolic and mental disorders. Although programmed changes in gene expression via epigenetic factors are hypothesized to regulate experience-dependent phenotypes, the mechanisms regulating the establishment and maintenance of these gene expression changes until adulthood are largely uncharacterized. My lab uses the animal model organism C. elegans and a variety of genetic, imaging, bioinformatic, behavioral, and molecular biology techniques to investigate the mechanisms of environmental programming of gene expression and its impact on adult phenotypes. Currently, my research focus is how animals use endogenous RNAi pathways to regulate gene expression and chromatin states in response to early environmental and developmental experiences.