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Polly Fordyce

Assistant Professor
genetics
Canary Center at Stanford
United States of America

Academician Genetics
Biography

Polly Fordyce is an Assistant Professor in the Genetics Department at Stanford, as well as a Faculty Fellow in ChEM-H. Her lab will focus on using microfluidic tools to make quantitative measurements of transcription factor specificity and developing new tools to allow the creation of large peptide and combinatorial chemistry libraries. Polly earned her PhD in the Physics Department at Stanford for single-molecule studies of kinesin family proteins in Steve Block's laboratory. As a postdoctoral fellow, she worked in Joe DeRisi's laboratory at UCSF developing microfluidic tools for characterizing transcription factor binding and using them to characterize proteins from both yeast and humans. She is starting her own lab at Stanford in September 2014.

Research Intrest

developing new instrumentation and assays for making quantitative, systems-scale biophysical measurements of molecular interactions

List of Publications
Nelson CS, Fuller CK, Fordyce PM, Greninger AL, Li H, DeRisi JL. Microfluidic affinity and ChIP-seq analyses converge on a conserved FOXP2-binding motif in chimp and human, which enables the detection of evolutionarily novel targets. Nucleic acids research. 2013 Jul 1;41(12):5991-6004.
Pérez JC, Fordyce PM, Lohse MB, Hanson-Smith V, DeRisi JL, Johnson AD. How duplicated transcription regulators can diversify to govern the expression of nonoverlapping sets of genes. Genes & development. 2014 Jun 15;28(12):1272-7.
Pérez JC, Fordyce PM, Lohse MB, Hanson-Smith V, DeRisi JL, Johnson AD. How duplicated transcription regulators can diversify to govern the expression of nonoverlapping sets of genes. Genes & development. 2014 Jun 15;28(12):1272-7.
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