Olof Eriksson

Researcher
Medicinal Chemistry, Organic Pharmaceutical Chemistry
Uppsala Biomedical Centre
Sweden

Biography

My basic education is a M.Sc. in Bioengineering from Chalmers University of Technology. I performed my Ph.D. in the field of Radiology at Uppsala University where I developed PET based methods for tracking transplanted insulin-producing cells in the living body. I performed my postdoctoral training at the Preclinical PET Platform at the department of Medicinal Chemistry, also at Uppsala University. During this period I started my own research group which currently consists of two Ph.D. students. We are focused on developing new methodologies for studying molecular processes inside the human body involved in the development and treatment of diabetes. A second track is to develop targeted probes for diagnosis and treatment of a certain form of neuroendocrine tumors with origin in the pancreatic beta cells. I am in parallel performing a second postdoctoral training period at Turku PET Center in Finland, which focuses on molecular imaging of brown adipose tissue - a form of adipose tissue which burns energy rather than stores it. It has long been known to be important to the energy metabolism in rodents but was only recently discovered in adult humans.

Research Intrest

Vivo molecular imaging, and positron emission tomography, new methods for diagnosis and radiotherapy of neuroendocrine tumors

List of Publications
Eich, T., Eriksson, O., Sundin, A., Estrada, S., Brandhorst, D. et al. (2007). Positron emission tomography: A real-time tool to quantify early islet engraftment in a preclinical large animal model. Transplantation, 84(7): 893-898
Eich, T., Eriksson, O., Lundgren, T. (2007). Visualization of early engraftment in clinical islet transplantation by positron-emission tomography. New England Journal of Medicin
Eriksson, O., Eich, T., Sundin, A., Tibell, A., Tufveson, G. et al. (2009). Positron emission tomography in clinical islet transplantation.
Selvaraju, R., Velikyan, I., Johansson, L., Wu, Z., Todorov, I. et al. (2013). In Vivo Imaging of the Glucagonlike Peptide 1 Receptor in the Pancreas with Ga-68-Labeled DO3A-Exendin-4.
Nalin, L., Selvaraju, R., Velikyan, I., Berglund, M., Andréasson, S. et al. (2014). Positron emission tomography imaging of the glucagon-like peptide-1 receptor in healthy and streptozotocin-induced diabetic pigs.
Eriksson, O., Velikyan, I., Selvaraju, R., Kandeel, F., Johansson, L. et al. (2014). Detection of Metastatic Insulinoma by Positron Emission Tomography with [(68)Ga]Exendin-4 -: a case report.
Eriksson, O., Selvaraju, R., Johansson, L., Eriksson, J., Sundin, A. et al. (2014). Quantitative Imaging of Serotonergic Biosynthesis and Degradation in the Endocrine Pancreas.

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