Michael Bassik

Assistant Professor
genetics
Canary Center at Stanford
United States of America

Academician Genetics
Biography

He is an assistant professor of Genetics and member of Bio-X and Stanford Cancer Institute. He is a Faculty Fellow of Stanford ChEM-H. He is a member of Stanford Neurosciences Institute.He did Ph.D. from Harvard University in Biological and Biomedical Sciences (2005)and B.S. from University of Wiscons,Madison in Biochemistry and Molecular Biology (1996).He is mainly focused in Endocytic pathogens such as protein aggregates, viruses, protein toxins, and bacteria have evolved remarkable ways to enter the cell, disrupt homeostasis, and cause cell death. We use these agents both as probes to understand normal cellular trafficking and signaling events, and to find key targets for therapy.

Research Intrest

Endocytic Pathogens as Tools and Targets

List of Publications
Leonardi W, Zilbermintz L, Cheng LW, Zozaya J, Tran SH, Elliott JH, Polukhina K, Manasherob R, Li A, Chi X, Gharaibeh D. Bithionol blocks pathogenicity of bacterial toxins, ricin, and Zika virus. Scientific reports. 2016 Sep 30;6:34475.
Duque-Afonso J, Lin CH, Han K, Wei MC, Feng J, Kurzer JH, Schneidawind C, Wong SH, Bassik MC, Cleary ML. E2A-PBX1 remodels oncogenic signaling networks in B-cell precursor acute lymphoid leukemia. Cancer research. 2016 Oct 7.
Hess GT, Frésard L, Han K, Lee CH, Li A, Cimprich KA, Montgomery SB, Bassik MC. Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells. Nature methods. 2016 Dec;13(12):1036.