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Mehdi Totonchi

Chief Researcher
Epigenetic Reprogramming
Royan Institute for Stem Cell Biology and Technology
Iran

Academician Molecular Biology
Biography

Mehdi Totonchi was born in 1979 in Badrood, Esfahan, Iran. He studied for a B.Sc in Biology at the University of Bu-Ali Sina in Hamedan from 1997-2002. In 2005, he received his M.Sc in the field of Molecular Genetics at Azad University of Research Sciences. For the next three years, he was a research assistant in the Department of Genetics and Stem Cells at Royan Institute. There, he was involved in the generation of the first induced pluripotent stem cell (iPSC) in Iran. In 2013, he finished his PhD at the joint program of the University of Science and Culture and Royan Institute in the field of Developmental Biology.

Research Intrest

Developmental Biology

List of Publications
Progress and promise towards safe induced pluripotent stem cells for therapy. Seifinejad A, Tabebordbar M, Baharvand H, Boyer LA, Salekdeh GH. Stem Cell Rev. 2010 Jun;6(2):297-306.
Human cardiomyocytes with long-QT syndrome in dish. Seifinejad A, Baharvand H. Arch Iran Med. 2010 Nov;13(6):573-5. No abstract available.
Generation of liver disease-specific induced pluripotent stem cells along with efficient differentiation to functional hepatocyte-like cells. Ghodsizadeh A, Taei A, Totonchi M, Seifinejad A, Gourabi H, Pournasr B, Aghdami N, Malekzadeh R, Almadani N, Salekdeh GH, Baharvand H. Stem Cell Rev. 2010 Dec;6(4):622-32.
Human-induced pluripotent stem cells: Derivation, propagation, and freezing in serum- and feeder layer-free culture conditions. Baharvand H, Totonchi M, Taei A, Seifinejad A, Aghdami N, Salekdeh GH. Methods Mol Biol. 2010;584:425-43.
Feeder- and serum-free establishment and expansion of human induced pluripotent stem cells. Totonchi M, Taei A, Seifinejad A, Tabebordbar M, Rassouli H, Farrokhi A, Gourabi H, Aghdami N, Hosseini-Salekdeh G, Baharvand H. Int J Dev Biol. 2010;54(5):877-86.
Generation of human induced pluripotent stem cells from a Bombay individual: Moving towards “universal-donor” red blood cells. Seifinejad A, Taei A, Totonchi M, Vazirinasab H, Hassani SN, Aghdami N, Shahbazi E, Yazdi RS, Salekdeh GH, Baharvand H. Biochem Biophys Res Commun. 2010 Jan 1;391(1):329-34.
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