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Mahmoud Salama

Lecturer of Pharmaceutical Chemistry and Drug
Pharmacology Department
British University in Egypt
Egypt

Academician Pharmaceutical Sciences
Biography

Education History: PhD in Organic Chemistry (2009- December 2013) South Dakota State University Brookings, South Dakota, United States of America Dissertation Title: Design, Synthesis, and Biological Screening of Cucurbitacin and Estrone Analogs towards Treatment of Melanoma. B.Sc. of Pharmaceutical Sciences (2000-2005) School of Pharmacy, Helwan University Cairo, Egypt Bio: A professional medicinal chemist with academic and research experience with over eight years of experience in lead optimization, molecular modeling drug design, process chemistry, method development, Chemistry of natural products, Heterocyclic Chemistry, Structural elucidation, bioassay guided fractionation, and in vitro biological screening.

Research Intrest

1- Computer Aided Drug Design 2- Outlining synthetic schemes and methodology optimization 3- Structure based drug design / pharmacophore based drug design 4- Stemistry (engagment of stem cell along with medicinal chemistry) 5- Computational repositioning of approved drugs for new clinical indications

List of Publications
Kopel LC, Ahmed MS, Halaweish FT. Synthesis of novel estrone analogs by incorporation of thiophenols via conjugate addition to an enone side chain. Steroids. 2013 Nov 30;78(11):1119-25.
Ahmed MS, Halaweish FT. Cucurbitacins: potential candidates targeting mitogen-activated protein kinase pathway for treatment of melanoma. Journal of enzyme inhibition and medicinal chemistry. 2014 Apr 1;29(2):162-7.
Ahmed MS, Kopel LC, Halaweish FT. Structural Optimization and Biological Screening of a Steroidal Scaffold Possessing Cucurbitacin‐Like Functionalities as B‐Raf Inhibitors. ChemMedChem. 2014 Jul 1;9(7):1361-7.

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