Team leader
Biomedical Research New Technologies
Centro de Investigacion Principe Felipe
Spain
Joaquín Dopazo obtained his PhD in Biology at the University of Valencia in 1989. After several appointments in different research centers he worked for 5 years in Glaxo Wellcome (now Glaxo SmithKline) during the late nineties. There he was developing methods for bacterial genomic analysis and he participated in several bacterial and fungal genome projects. In 2000 he moved to the Spanish National Cancer Center (CNIO), where he set up the Bioinformatics group. In the CNIO he designed the first Spanish microarray (the Oncochip) in 2000 and he developed the most used resource for microarray data analysis on the web (GEPAS), now discontinued and included in the Babelomics, one of the most used resources for genomic data analysis and interpretation (cited more than 1500 times). The scope of the algorithms and software developed has evolved currently to the field of massive sequence data analysis
The main lines of research is to relate variation at genomic level (punctual or structural variants, methylation changes, gene expression differences, etc.) to their effect at both cellular and phenotypic level trying to understand the underlying mechanisms that govern the network of molecular interactions in the cell.