I George Miller

Jr, MD John F. Enders Professor of Pediatrics (Inf
Pediatrics (Infectious Disease)
Yale School of Public Health
United States of America

Academician Infectious Diseases
Biography

Dr. Miller’s laboratory studies the mechanisms underlying the switch between latency and lytic replication of two oncogenic herpesviruses, Epstein-Barr virus and Kaposi’s sarcoma-associated herpesvirus. Current experiments explore how viral and cellular transcription factors that selectively bind to methylated DNA control expression of viral and cellular genes, how cellular gene expression is selectively inhibited while viral gene expression is enhanced, and how viral DNA replication is regulated by cellular proteins. Recent studies focus on a new class of anti-viral agents that inhibit reactivation of Epstein-Barr virus from latency into lytic infection. Education & Training AB in Harvard College (1968) MD in Harvard Medical School (1962) Research Fellow in Children's Hospital, Boston Research Fellow in Harvard Medical School Intern & Assistant Resident in University Hospital, Cleveland.

Research Intrest

Pediatrics (Infectious Disease).