Gen Suzuki

Associate Professor
Department of Medicine
Buffalo VA Medical Center
United States of America

Academician Cardiology
Biography

Gen Suzuki a researcher with formal training and practice in both general and interventional cardiology. His research expertise is in coronary physiology and physiological studies in large animals with ischemic heart disease. Based on his background, research is focused on therapeutic approaches to effect cardiac regeneration in large animals with acute and chronic ischemic heart disease. Education and Training: FAHA, American Heart Association Council on Basic Cardiovascular Sciences (2011), PhD, Akita University Graduate School of Medicine (1998), MD, Akita University School of Medicine (1992). He routinely perform physiological studies on these porcine models with quantitative analyses of myocardial morphometry and immune-histochemical analyses. His current work is focused on understanding the regenerative capability of cardiosphere-derived cells (CDCs) originating from heart tissue in acute or chronic ischemic myocardium. The result of this work will play an important role in advancing the care of many patients with acute and chronic ischemic heart disease. Awards and Honors: Buswell Fellow (2007), AHA BCVS Travel Award (2003). In his laboratory, he use a preclinical porcine model of hibernating myocardium with chronic left anterior descending (LAD) coronary artery occlusion and collateral-dependent myocardium or infarcted myocardium caused by coronary ischemia-reperfusion.

Research Intrest

Apoptosis and cell death; Cardiology; Cardiovascular Disease; Cell Cycle; Cell growth, differentiation and development; Gene therapy; Internal Medicine; Stem Cells

List of Publications
Leiker M, Suzuki G, Iyer VS, Canty Jr JM, Lee T. Assessment of a nuclear affinity labeling method for tracking implanted mesenchymal stem cells. Cell transplantation. 2008 Aug 1;17(8):911-22.
Zisa D, Shabbir A, Suzuki G, Lee T. Vascular endothelial growth factor (VEGF) as a key therapeutic trophic factor in bone marrow mesenchymal stem cell-mediated cardiac repair. Biochemical and biophysical research communications. 2009 Dec 18;390(3):834-8.
Shabbir A, Zisa D, Lin H, Mastri M, Roloff G, Suzuki G, Lee T. Activation of host tissue trophic factors through JAK-STAT3 signaling: a mechanism of mesenchymal stem cell-mediated cardiac repair. American Journal of Physiology-Heart and Circulatory Physiology. 2010 Nov 1;299(5):H1428-38.