Christopher Raub

Assistant Professor
School of Enginerring
Catholic University of America
United States of America

Academician Biomedical Sciences
Biography

Ph.D., Biomedical Engineering, University of California, Irvine, 2009 M.S., Biomedical Engineering, University of California, Irvine, 2006 B.S., Biology, Harvey Mudd College, 2004. Dr. Raub’s research goal is to determine microscale mechanisms of tissue injury, remodeling, and repair, with insights that lead to novel diagnostic and therapeutic strategies. To achieve this objective, Dr. Raub’s laboratory is designed to merge tissue engineering, biomedical optics, and microfluidics to noninvasively capture cell and matrix dynamics in 3-D, and relate microscale features to macroscale tissue mechanics. Using similar approaches in the past, Dr. Raub has analyzed the influence of extracellular matrix microstructure on bulk mechanical properties of engineered tissue, pulmonary airways following epithelial injury, and articular cartilage during knee joint degeneration and surgical repair. This work occurred during his doctoral studies at the University of California, Irvine, from 2004-2009, and his postdoctoral work at the University of California, San Diego, from 2009-2013. From 2013-2014, Dr. Raub pursued a capstone postdoctoral experience at the Keck School of Medicine, University of Southern California, developing microfluidic assays for the detection of cancer mutations. Moving forward, the unifying theme of Dr. Raub’s research will be noninvasive assessment of and control over cell and matrix dynamics to inhibit pathologic and guide therapeutic remodeling of collagen-rich tissues.

Research Intrest

Microscale mechanisms of tissue injury, remodeling, and repair, with insights that lead to novel diagnostic and therapeutic strategies.

List of Publications
Malavia NK, Mih JD, Raub CB, Dinh BT, George SC. IL-13 induces a bronchial epithelial phenotype that is profibrotic. Respiratory research. 2008 Mar 18;9(1):27.
Raub CB, Mahon S, Narula N, Tromberg BJ, Brenner M, George SC. Linking optics and mechanics in an in vivo model of airway fibrosis and epithelial injury. Journal of biomedical optics. 2010 Jan 1;15(1):015004-.
Raub CB, Hsu SC, Chan EF, Shirazi R, Chen AC, Chnari E, Semler EJ, Sah RL. Microstructural remodeling of articular cartilage following defect repair by osteochondral autograft transfer. Osteoarthritis and cartilage. 2013 Jun 30;21(6):860-8.