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Charles R. Vinson

Senior Investigator
Gene Regulation
Laboratory of Metabolism National Cancer Institute Center for Cancer Research
United States of America

Academician Genetics
Biography

Dr. Charles Vinson received his Ph.D. from the University of Virginia studying Drosophila developmental genetics with Dr. Paul Adler. He subsequently carried out postdoctoral work at the Carnegie Institution of Washington in Baltimore, MD, with Dr. Steven McKnight, and joined the NCI as a tenure track fellow in 1991.

Research Intrest

Transcription factors, Coiled-coil, CG methylation, DNA binding

List of Publications
Caravaca JM, Donahue G, Becker JS, He X, Vinson C, Zaret KS. Bookmarking by specific and nonspecific binding of FoxA1 pioneer factor to mitotic chromosomes. Genes & development. 2013 Feb 1;27(3):251-60.
Gao R, Das BB, Chatterjee R, Abaan OD, Agama K, Matuo R, Vinson C, Meltzer PS, Pommier Y. Epigenetic and genetic inactivation of tyrosyl-DNA-phosphodiesterase 1 (TDP1) in human lung cancer cells from the NCI-60 panel. DNA repair. 2014 Jan 31;13:1-9.
Chen ZX, Sturgill D, Qu J, Jiang H, Park S, Boley N, Suzuki AM, Fletcher AR, Plachetzki DC, FitzGerald PC, Artieri CG. Comparative validation of the D. melanogaster modENCODE transcriptome annotation. Genome research. 2014 Jul 1;24(7):1209-23.
Golla JP, Zhao J, Mann IK, Sayeed SK, Mandal A, Rose RB, Vinson C. Carboxylation of cytosine (5caC) in the CG dinucleotide in the E-box motif (CGCAG| GTG) increases binding of the Tcf3| Ascl1 helix-loop-helix heterodimer 10-fold. Biochemical and biophysical research communications. 2014 Jun 27;449(2):248-55.
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