Assistant Professors
Hematology
University of Miami Health System
Canada
The immunological response of T cells in allogenic stem cell transplants (SCT) plays a critical role in the success or failure of the hematological graft. Using data generated by 10+ color flow cytometry in Dr. Komanduri’s lab to define cytokine and chemokine production of the subsets of CD4+ and CD8+ T cells we have a better understanding of which maturation stage of cells are participating in the engraftment or rejection process. Understanding how the fine subsets of T cells participate in immunologic function in human disease will support our goal of developing more selective strategies of immunosuppression and T cell targeting to improve the outcomes in the setting of SCT in humans.