Cara Benjamin

Assistant Professors
Hematology
University of Miami Health System
Canada

Academician Haematology
Biography

Cara Benjamin a Assistant Professors of Medicine in the department of Hematology/Oncology from The University of Miami Health System Cara Benjamin a Assistant Professors of Medicine in the department of Hematology/Oncology from The University of Miami Health System

Research Intrest

The immunological response of T cells in allogenic stem cell transplants (SCT) plays a critical role in the success or failure of the hematological graft. Using data generated by 10+ color flow cytometry in Dr. Komanduri’s lab to define cytokine and chemokine production of the subsets of CD4+ and CD8+ T cells we have a better understanding of which maturation stage of cells are participating in the engraftment or rejection process. Understanding how the fine subsets of T cells participate in immunologic function in human disease will support our goal of developing more selective strategies of immunosuppression and T cell targeting to improve the outcomes in the setting of SCT in humans.  

List of Publications
Shindo, T., Kim, T.K., Benjamin. C.L., Wieder, E.D., Levy, R.B., and Komanduri, K.V. MEK inhibitors selectively suppress alloreactivity and graft-versus-host disease in a memory stage-dependent manner. Blood. Jun 6;121(23):4617-26. 2013.
Komanduri, K.V., Wieder, E.D., Benjamin, C.L., and Levy, RB. The evolving art of hematopoietic stem cell transplantation: translational research in post-transplant immune reconstitution and immunosuppression. Immunol Res. 2013 Dec;57(1-3):140-50
Parikh, S.H., Mendizabal, A., Benjamin, C.L., Komanduri, K.V., Antony, J., Petrovic, A., Hale, G., Driscoll, T.A., Martin, P.L., Page, K.M., Flickinger, K., Moffet, J., Niedwiecki, F., Kurtzberg, J., and Szabolcs, P. A Novel Reduced-Intensity Conditioning Regimen for Unrelated Umbilical Cord Blood Transplantatiopn in Children with Nonmalignant Diseases. Biol Blood Marrow Tranplant. 2013 Dec 1. doi; 10.1016/j.bbmt.2013.11.021.