Angela Gutchess

Associate Professor of Psychology
Neuroscience, Psychology
Brandeis University
United States of America

Academician Neurology
Biography

Research in her laboratory explores the effects of age and culture on memory and social processes using functional magnetic resonance imaging (fMRI) and behavioral measures. Her research on aging and memory explores age differences in the specificity and accuracy of memory and in the plasticity of the neural resources that subserve memory processes. Her previous research demonstrates that older adults can compensate for decreased medial temporal lobe activity by recruiting regions of prefrontal cortex to support encoding. However, age differences occur at the time of recognition in prefrontal regions when contexts interfere with the recognition of studied objects and in widespread brain regions when similar lures must be distinguished from studied pictures. Her current work addresses the specificity of memory processes by exploring the extent to which 1) age-related deficits occur due to a failure to engage sensory or controlled processes, and 2) the loss of specificity and compensatory mechanisms documented with age for sensory domains also characterizes social domains, functions that are purportedly preserved with age. Her research on cross-cultural differences compares cognitive and social processes across East Asian and Western cultures. Her previous fMRI research demonstrates that culture affects object processing, with Americans engaging object-specific regions to a greater extent than East Asians during the encoding of complex scenes. She also explored the interaction of culture and aging, a line of work that pits the influence of life experiences and plasticity against neurobiological aging. We’ve identified cultural differences in the use of categories to organize memory for older, but not younger, adults. Our current work continues to address these themes, exploring the specificity of memory processes for cognitive and social domains, using both behavioral and neuroimaging methods. Although cultures may differ across these domains in the specificity of the details encoded into memory, aging is predicted to reduce the specificity of memory processes, thus eliminating cross-cultural differences.

Research Intrest

Effects of age and culture on memory; Cognitive and Social Neuroscience

List of Publications
Paige LE, Ksander JC, Johndro HA, Gutchess AH. Cross-cultural differences in the neural correlates of specific and general recognition. Cortex. 2017 Jun 30;91:250-61.
Luther JA, Birren SJ. Co-Release of Norepinephrine and Acetylcholine by Mammalian Sympathetic Neurons: Regulation by Target-Derived Signaling. InCo-Existence and Co-Release of Classical Neurotransmitters 2009 (pp. 1-19). Springer US.
Auslander MV, Thomas AK, Gutchess AH. Confidence Moderates the Role of Control Beliefs in the Context of Age-Related Changes in Misinformation Susceptibility. Experimental Aging Research. 2017 May 27;43(3):305-22.