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Experts in Genetics
Sanjay Gupta David Buchanan Drena Dobbs Karin S Dorman Dr. Xun Gu Thomas Peterson IRFAN AHMAD ANSARI John Golin Jannice Friedman Vimla Aggarwal Andrea Rinaldi Carmen Argmann Eleanor Maine Albertini Alessandra Judith Greenberg Mark Clark John F. Hayes Ashok Kumar Roger I. Cue PETER LIN View MoreAimée M. Dudley
Dudley Lab
Pacific Northwest National Laboratory
United States of America
Research in the Dudley lab focuses on two areas: developing new methods to predict an organism’s response to genetic or environmental perturbations and deciphering the novel biology uncovered by applying them. The genotype-phenotype problem is among the most fundamental in biology. Given the complete genome sequence of an individual, can we predict what traits they will exhibit? The emerging field of systems genetics seeks to solve this problem by integrating the principles and technologies of systems biology with genetic analysis. Together with our collaborators, we are applying systems genetics to understand complex traits, such as the predisposition to disease and response to therapeutics. Our work is conducted in the yeast Saccharomyces cerevisiae, which was the first fully sequenced eukaryotic organism and has been key to the development of every major “omic” tool to date. Below are brief descriptions of some of our research interests and ongoing projects.
genetic or environmental perturbations